• What is Pinkeye?
• Economic cost
• Predisposing factors
• Clinical signs
• Treatment
• Prevention

• Mode of action
• Dose rate & administration
• Vaccination schedule
• Efficacy & safety
• Cross-reactivity
• Why vaccinate?
• OH&S
• Product lnformation

Efficacy & Safety

• Coopers Piliguard Pinkeye-1 Trivalent Vaccine has been available internationally    for over 15 years (first registered in the USA in 1990, New Zealand and South
   Africa in 2000) and the safety and efficacy of the vaccine is accepted    worldwide. Over 25 million doses have been sold in the USA alone in the last 8    years


• Being an oil adjuvanted vaccine, a transient local reaction can sometimes
   occur at the injection site – this reaction should subside over a period of
   2-6 weeks


• The efficacy of Piliguard has been proven internationally by controlled challenge
   studies, field trials and serology testing of vaccinated calves:


           - In 1990 a challenge study was performed to determine the efficacy of a              single dose 3 strain Moraxella bovis vaccine³.


           - 94 calves were used in the study – 45 vaccinated and 49 unvaccinated
             controls. Calves were separated into groups and then exposed to one of              the three strains of M. bovis

           - Across these groups only 5 out of 45 of the vaccinated calves developed              clinical signs of pinkeye, whereas in the unvaccinated calves 30 out of 49              calves developed clinical signs


           - The study concluded that a single dose 3 strain Moraxella bovis vaccine              provided significant protection against M. bovis



                             

• Coopers Piliguard Trivalent-1 Pinkeye Vaccine has been shown to be relevant to    the local Australian strains of M. bovis by in vitro immunogenic correlation


• Disease challenge studies have not been performed on any live animals in    Australia, due to ethical reasons and the strong supporting international data


• After extensive international use for almost two decades, there is no information    available to indicate that the administration of Coopers Piliguard vaccine has    any potential to adversely affect reproductive performance